The postnatal decline of hemoglobin F synthesis in normal full-term infants.

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The postnatal decline of hemoglobin F synthesis in normal full-term infants.

Studies were carried out during the 1st yr of life in normal infants born at term to determine the proportions of fetal hemoglobin (Hb F) and adult hemoglobin (Hb A) being synthesized, in order to describe the complete switchover from Hb F to Hb A synthesis during postnatal life. 53 blood samples from 37 infants were incubated in an amino acid mixture containing [14C]leucine and chromatographed...

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comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.

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Postnatal Fetal and Adult Hemoglobin Synthesis in Preterm Infants Whose Birth

A B S T R A C T To determine if environmental factors could effect the switchover from fetal hemoglobin (HbF) to adult hemoglobin (HbA) synthesis, studies were carried out on blood samples from eight infants born at <1,000 g, when they had reached their postconceptional age corresponding to term. All of these infants required prolonged intensive care, multiple blood transfusions, and two requir...

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Postnatal fetal and adult hemoglobin synthesis in early preterm newborn infants.

Studies were carried out during the postnatal period in infants born at or before the 32nd wk of gestation to determine the proportion of fetal hemoglobin (Hb F) and adult hemoglobin (Hb A) being synthesized, and to compare these studies to those previously reported on at birth from normal newborn infants 25-43 wk gestation. When the pretern infants reached the postconceptional age correspondin...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1975

ISSN: 0021-9738

DOI: 10.1172/jci107943